CJC-1295 No DAC vs DAC, why it's the same as Modified GRF(1-29), and what to look for when sourcing it in the UK at ≥99% purity. For in-vitro research use only.
CJC-1295 comes up constantly in growth-hormone-pathway research, but it's also one of the more frequently confused peptides — mostly because of the "DAC / No DAC" distinction. This guide clears that up and explains what to look for when sourcing the No-DAC version in the UK, for in-vitro research only.
What CJC-1295 (No DAC) actually is
CJC-1295 without DAC is a modified fragment of growth-hormone-releasing hormone — specifically a stabilised version of GRF(1-29), the active 29-amino-acid portion of GHRH. It's often listed simply as Modified GRF(1-29), and that's the same compound.
The important point is the "No DAC" part. DAC stands for Drug Affinity Complex, a modification that dramatically extends a peptide's half-life. The No-DAC version doesn't carry it, so in research models it shows a much shorter, more pulsatile signalling profile. The two are genuinely different tools — and it's worth being precise, because a lab logging its materials will notice if the label and the behaviour don't match.
UKPeptides supplies CJC-1295 (No DAC) at ≥99% HPLC purity, with a batch-specific Certificate of Analysis on every order.
Where it's used
In laboratory work, CJC-1295 (No DAC) is studied for:
- GHRH-receptor signalling in endocrine models
- Growth-hormone-secretagogue pathway research
- Comparative studies alongside ghrelin-receptor agonists such as ipamorelin
It is supplied for research only, not for human or veterinary use.
Why the paperwork matters
Because GHRH analogues are easy to mislabel and the No-DAC and DAC versions look identical as a powder, the Certificate of Analysis does double duty here: the mass-spec result confirms you have the right molecule, and the HPLC trace confirms it's clean. If you're unsure what a good certificate should contain, our guide to reading a COA breaks it down.
Every batch we release is verified at an independent accredited laboratory, and the COA that ships with your order matches the specific lot number on the vial.
Handling
CJC-1295 (No DAC) arrives lyophilised and is reconstituted before use, typically with bacteriostatic water. Add the solvent gently, let the cake dissolve without shaking, and keep the made-up solution cold and out of the light. The full method is in our reconstitution guide.
Sourcing in the UK
Look for the essentials: ≥99% HPLC purity, a batch-specific COA, cold-chain dispatch, and clear labelling that names the compound correctly — No DAC, not DAC.
UKPeptides stocks CJC-1295 (No DAC) at ≥99% purity, with free cold-chain UK delivery and same-day dispatch before 3 pm GMT.
For research use only. This article is educational and does not describe human, clinical or veterinary use.
Written and reviewed to our editorial standards. Explore the research peptide catalog or read more in Research Notes.
For research use only · Not for human or veterinary use
